4e2i: Difference between revisions

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[[Image:4e2i.jpg|left|200px]]
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{{STRUCTURE_4e2i|  PDB=4e2i  |  SCENE=  }}  
{{STRUCTURE_4e2i|  PDB=4e2i  |  SCENE=  }}  
===The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase===
===The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase===
{{ABSTRACT_PUBMED_22700977}}


==Function==
[[http://www.uniprot.org/uniprot/DPOA2_HUMAN DPOA2_HUMAN]] May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).


==About this Structure==
==About this Structure==
[[4e2i]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Simian_virus_40 Simian virus 40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2I OCA].  
[[4e2i]] is a 23 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Simian_virus_40 Simian virus 40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E2I OCA].  
==See Also==
*[[DNA polymerase|DNA polymerase]]
==Reference==
<ref group="xtra">PMID:022700977</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Simian virus 40]]
[[Category: Simian virus 40]]

Revision as of 04:58, 28 August 2013

Template:STRUCTURE 4e2i

The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase

Template:ABSTRACT PUBMED 22700977

Function

[DPOA2_HUMAN] May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).

About this Structure

4e2i is a 23 chain structure with sequence from Homo sapiens and Simian virus 40. Full crystallographic information is available from OCA.

See Also

Reference

  1. Zhou B, Arnett DR, Yu X, Brewster A, Sowd GA, Xie CL, Vila S, Gai D, Fanning E, Chen XS. Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase. J Biol Chem. 2012 Aug 3;287(32):26854-66. doi: 10.1074/jbc.M112.363655. Epub 2012, Jun 14. PMID:22700977 doi:10.1074/jbc.M112.363655

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