Sandbox Mati: Difference between revisions

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<scene name='43/437742/2yxj_glu/2'>two negativly charged residues</scene> Glu 96 and Glu 129.
<scene name='43/437742/2yxj_glu/2'>two negativly charged residues</scene> Glu 96 and Glu 129.
Two <scene name='43/437742/2yxj_hydrophobic/1'>hydrophobic patches</scene> which include Phe 191 Val 141 and  
Two <scene name='43/437742/2yxj_hydrophobic/1'>hydrophobic patches</scene> which include Phe 191 Val 141 and  
Ala 93 for one, and the other patch includes Phe 146 Val 126 and Leu 108.Now one can look at the  <scene name='43/437742/2yxj_space_fill_color_charged/1'>Overall</scene> picture that there is negatively charge residues "above" and "below" the lignd and a posite charge on the "right" and "left" of it.
Ala 93 for one, and the other patch includes Phe 146 Val 126 and Leu 108.Now one can look at the  <scene name='43/437742/2yxj_space_fill_color_charged/1'>Overall</scene> picture that there is hydropobic patches  "above" and "below" the ligand ,negatively charged residues "above-right" and "below-left" of the ligand and positivly charges on the "right" and "left" of it.
This symmetry can be an entropic advantage by designing a symmetric molecule.