4jhz: Difference between revisions
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{{STRUCTURE_4jhz| PDB=4jhz | SCENE= }} | |||
===Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide=== | |||
{{ABSTRACT_PUBMED_23690068}} | |||
==About this Structure== | |||
[[4jhz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JHZ OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023690068</ref><references group="xtra"/><references/> | |||
[[Category: Beta-glucuronidase]] | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Redinbo, M R.]] | |||
[[Category: Roberts, A B.]] | |||
[[Category: Wallace, B D.]] | |||
[[Category: Alpha/beta barrel]] | |||
[[Category: Beta-sandwich domain]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Sugar-binding domain]] | |||
Revision as of 07:31, 28 August 2013
Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide
Template:ABSTRACT PUBMED 23690068
About this Structure
4jhz is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Roberts AB, Wallace BD, Venkatesh MK, Mani S, Redinbo MR. Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity. Mol Pharmacol. 2013 Aug;84(2):208-17. doi: 10.1124/mol.113.085852. Epub 2013 May , 20. PMID:23690068 doi:10.1124/mol.113.085852
