3w97: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region===

~~The entry 3w97~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>

~~Authors~~: ~~Iwasaki, W~~.~~, Miya, Y~~.~~, Horikoshi, N~~.~~, Osakabe, A., Tachiwana, H~~.~~, Shibata, T~~.~~, Kagawa, W~~.~~, Kurumizaka, H~~.

==About this Structure==

[[3w97]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W97 OCA].

~~Description~~:

==Reference==

[[Category: Homo sapiens]]

[[Category: Horikoshi, N.]]

[[Category: Iwasaki, W.]]

[[Category: Kagawa, W.]]

[[Category: Kurumizaka, H.]]

[[Category: Miya, Y.]]

[[Category: Osakabe, A.]]

[[Category: Shibata, T.]]

[[Category: Tachiwana, H.]]

[[Category: Histone-fold]]

[[Category: Nucleosome]]

[[Category: Protein-dna complex]]

[[Category: Structural protein-dna complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3w97|  PDB=3w97  |  SCENE=  }}
+===Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region===
-The entry 3w97 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>   Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>
-Authors: Iwasaki, W., Miya, Y., Horikoshi, N., Osakabe, A., Tachiwana, H., Shibata, T., Kagawa, W., Kurumizaka, H.
+==About this Structure==
+[[3w97]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W97 OCA].
-Description:
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Horikoshi, N.]]
+[[Category: Iwasaki, W.]]
+[[Category: Kagawa, W.]]
+[[Category: Kurumizaka, H.]]
+[[Category: Miya, Y.]]
+[[Category: Osakabe, A.]]
+[[Category: Shibata, T.]]
+[[Category: Tachiwana, H.]]
+[[Category: Histone-fold]]
+[[Category: Nucleosome]]
+[[Category: Protein-dna complex]]
+[[Category: Structural protein-dna complex]]