3u1a: Difference between revisions
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{{STRUCTURE_3u1a| PDB=3u1a | SCENE= }} | {{STRUCTURE_3u1a| PDB=3u1a | SCENE= }} | ||
===N-terminal 81-aa fragment of smooth muscle tropomyosin alpha=== | ===N-terminal 81-aa fragment of smooth muscle tropomyosin alpha=== | ||
{{ | {{ABSTRACT_PUBMED_22119916}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/TPM1_CHICK TPM1_CHICK]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Tropomyosin|Tropomyosin]] | *[[Tropomyosin|Tropomyosin]] | ||
==Reference== | |||
<ref group="xtra">PMID:022119916</ref><references group="xtra"/><references/> | |||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Dominguez, R.]] | [[Category: Dominguez, R.]] | ||
Revision as of 09:15, 4 September 2013
N-terminal 81-aa fragment of smooth muscle tropomyosin alpha
Template:ABSTRACT PUBMED 22119916
Function
[TPM1_CHICK] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
About this Structure
3u1a is a 4 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Rao JN, Rivera-Santiago R, Li XE, Lehman W, Dominguez R. Structural analysis of smooth muscle tropomyosin alpha and beta isoforms. J Biol Chem. 2012 Jan 27;287(5):3165-74. Epub 2011 Nov 27. PMID:22119916 doi:10.1074/jbc.M111.307330
