4gmi: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4gmi|  PDB=4gmi  |  SCENE=  }}
+===BACE-1 in complex with HEA-type macrocyclic inhibitor, MV078571===
-The entry 4gmi is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/BACE1_HUMAN BACE1_HUMAN]] Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.<ref>PMID:10677483</ref> <ref>PMID:20354142</ref>
-Authors: Lindberg, J.D., Derbyshire, D.
+==About this Structure==
+[[4gmi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMI OCA].
-Description: BACE-1 in complex with HEA-type macrocyclic inhibitor, MV078571
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Memapsin 2]]
+[[Category: Derbyshire, D.]]
+[[Category: Lindberg, J D.]]
+[[Category: Asp2]]
+[[Category: Bace]]
+[[Category: Bace-1]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Macrocycle]]

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