Biological Unit: Difference between revisions

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==Sources of Biological Unit Models==
==Sources of Biological Unit Models==
===Unreliability of REMARK 350 in the PDB File Header===
When a structure is deposited in the [[PDB]], the authors are required to specify the biological unit if it is known. This is given in REMARK 350 in the header of the [[PDB file]]. Unfortunately, information in REMARK 350 is often incorrect (see [https://lists.sdsc.edu/pipermail/pdb-l/2013-June/005836.html discussion of this problem by Roland Dunbrack]). There are numerous examples in which the authors state that the biological unit is a monomer in REMARK 350, but provide good experimental evidence in the paper reporting the structure that the biological unit is a dimer. Jose Duarte provided a [https://lists.sdsc.edu/pipermail/pdb-l/2013-June/005834.html list of examples].


===REMARK 350 in the PDB File Header===
===REMARK 350 in the PDB File Header===