4btl: Difference between revisions
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{{STRUCTURE_4btl| PDB=4btl | SCENE= }} | |||
===Aromatic interactions in acetylcholinesterase-inhibitor complexes=== | |||
{{ABSTRACT_PUBMED_23984975}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. | |||
==About this Structure== | |||
[[4btl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BTL OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023984975</ref><references group="xtra"/><references/> | |||
[[Category: Acetylcholinesterase]] | |||
[[Category: Mus musculus]] | |||
[[Category: Akfur, C.]] | |||
[[Category: Allgardsson, A.]] | |||
[[Category: Andersson, C D.]] | |||
[[Category: Berg, L.]] | |||
[[Category: Ekstrom, F.]] | |||
[[Category: Engdahl, C.]] | |||
[[Category: Forsgren, N.]] | |||
[[Category: Linusson, A.]] | |||
[[Category: Qian, W.]] | |||
[[Category: Acetylcholinesterase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Inhibitor]] | |||
Revision as of 05:25, 12 September 2013
Aromatic interactions in acetylcholinesterase-inhibitor complexes
Template:ABSTRACT PUBMED 23984975
Function
[ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
About this Structure
4btl is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian W, Ekstrom FJ, Linusson A. Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. J Med Chem. 2013 Aug 28. PMID:23984975 doi:10.1021/jm400990p