3ong: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3ong| PDB=3ong | SCENE= }} | {{STRUCTURE_3ong| PDB=3ong | SCENE= }} | ||
===Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways=== | ===Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways=== | ||
{{ABSTRACT_PUBMED_21209884}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/UBA2_YEAST UBA2_YEAST]] The dimeric enzyme acts as a SMT3 E1 ligase. It mediates ATP-dependent activation of SMT3 and formation of a thioester with a conserved cysteine residue on AOS1. [[http://www.uniprot.org/uniprot/UBC9_YEAST UBC9_YEAST]] E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2).<ref>PMID:9341106</ref> <ref>PMID:11572779</ref> | |||
==About this Structure== | ==About this Structure== | ||
| Line 12: | Line 11: | ||
==See Also== | ==See Also== | ||
*[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]] | *[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]] | ||
*[[Ubiquitin activating enzyme|Ubiquitin activating enzyme]] | |||
==Reference== | |||
<ref group="xtra">PMID:021209884</ref><references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Huang, D T.]] | [[Category: Huang, D T.]] | ||
