3m1h: Difference between revisions
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{{STRUCTURE_3m1h| PDB=3m1h | SCENE= }} | {{STRUCTURE_3m1h| PDB=3m1h | SCENE= }} | ||
===Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83=== | ===Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83=== | ||
{{ | {{ABSTRACT_PUBMED_21812842}} | ||
==Function== | ==Function== | ||
[[http://www.uniprot.org/uniprot/ | [[http://www.uniprot.org/uniprot/KGP83_PORGN KGP83_PORGN]] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2] | ||
==About this Structure== | ==About this Structure== | ||
[[3m1h]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3m1h]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis_w83 Porphyromonas gingivalis w83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M1H OCA]. | ||
[[Category: Porphyromonas gingivalis]] | |||
==Reference== | |||
<ref group="xtra">PMID:021812842</ref><references group="xtra"/><references/> | |||
[[Category: Porphyromonas gingivalis w83]] | |||
[[Category: Collyer, C A.]] | [[Category: Collyer, C A.]] | ||
[[Category: Hunter, N.]] | [[Category: Hunter, N.]] | ||
