4l5b: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4l5b|  PDB=4l5b  |  SCENE=  }}
+===Human dCK C4S-S74E mutant in complex with UDP and the DI-43 inhibitor===
+{{ABSTRACT_PUBMED_23947754}}
-The entry 4l5b is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/DCK_HUMAN DCK_HUMAN]] Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.<ref>PMID:18377927</ref> <ref>PMID:20614893</ref>
-Authors: Nomme, J., Lavie, A.
+==About this Structure==
+[[4l5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5B OCA].
-Description:
+==Reference==
+<ref group="xtra">PMID:023947754</ref><references group="xtra"/><references/>
+[[Category: Deoxycytidine kinase]]
+[[Category: Homo sapiens]]
+[[Category: Lavie, A.]]
+[[Category: Nomme, J.]]
+[[Category: Deoxycytidine kinase]]
+[[Category: Phosphoryl transfer]]
+[[Category: Phosphorylation]]
+[[Category: Transferase-transferase inhibitor complex]]

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