4ab3: Difference between revisions
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{{STRUCTURE_4ab3| PDB=4ab3 | SCENE= }} | {{STRUCTURE_4ab3| PDB=4ab3 | SCENE= }} | ||
===ATP-triggered molecular mechanics of the chaperonin GroEL=== | ===ATP-triggered molecular mechanics of the chaperonin GroEL=== | ||
{{ABSTRACT_PUBMED_22445172}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] | |||
==About this Structure== | ==About this Structure== | ||
[[4ab3]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AB3 OCA]. | [[4ab3]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AB3 OCA]. | ||
==See Also== | |||
*[[Chaperonin|Chaperonin]] | |||
==Reference== | |||
<ref group="xtra">PMID:022445172</ref><references group="xtra"/><references/> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Clare, D K.]] | [[Category: Clare, D K.]] | ||
Revision as of 06:48, 29 September 2013
ATP-triggered molecular mechanics of the chaperonin GroEL
Template:ABSTRACT PUBMED 22445172
Function
[CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
About this Structure
4ab3 is a 14 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR. ATP-triggered conformational changes delineate substrate-binding and -folding mechanics of the GroEL chaperonin. Cell. 2012 Mar 30;149(1):113-23. Epub 2012 Mar 22. PMID:22445172 doi:10.1016/j.cell.2012.02.047
