3h15: Difference between revisions
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{{STRUCTURE_3h15| PDB=3h15 | SCENE= }} | {{STRUCTURE_3h15| PDB=3h15 | SCENE= }} | ||
===Crystal structure of replication initiation factor MCM10-ID bound to ssDNA=== | ===Crystal structure of replication initiation factor MCM10-ID bound to ssDNA=== | ||
{{ABSTRACT_PUBMED_19608746}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MCM10_XENLA MCM10_XENLA]] Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication (By similarity).<ref>PMID:11864598</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019608746</ref><references group="xtra"/> | <ref group="xtra">PMID:019608746</ref><references group="xtra"/><references/> | ||
[[Category: Xenopus laevis]] | [[Category: Xenopus laevis]] | ||
[[Category: Eichman, B F.]] | [[Category: Eichman, B F.]] | ||
Revision as of 06:58, 29 September 2013
Crystal structure of replication initiation factor MCM10-ID bound to ssDNA
Template:ABSTRACT PUBMED 19608746
Function
[MCM10_XENLA] Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication (By similarity).[1]
About this Structure
3h15 is a 2 chain structure with sequence from Xenopus laevis. Full crystallographic information is available from OCA.
Reference
- Warren EM, Huang H, Fanning E, Chazin WJ, Eichman BF. Physical interactions between Mcm10, DNA, and DNA polymerase alpha. J Biol Chem. 2009 Sep 4;284(36):24662-72. Epub 2009 Jul 16. PMID:19608746 doi:10.1074/jbc.M109.020438
