4kn2: Difference between revisions
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{{STRUCTURE_4kn2| PDB=4kn2 | SCENE= }} | {{STRUCTURE_4kn2| PDB=4kn2 | SCENE= }} | ||
===Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed=== | ===Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed=== | ||
{{ABSTRACT_PUBMED_23934049}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4kn2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KN2 OCA]. | [[4kn2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KN2 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023934049</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: III, C E.Dann.]] | [[Category: III, C E.Dann.]] | ||
Revision as of 06:04, 2 October 2013
Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed
Template:ABSTRACT PUBMED 23934049
Function
[FOLR2_HUMAN] Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
About this Structure
4kn2 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE 3rd. Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15180-8. doi:, 10.1073/pnas.1308827110. Epub 2013 Aug 9. PMID:23934049 doi:10.1073/pnas.1308827110
