4l9o: Difference between revisions
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{{STRUCTURE_4l9o| PDB=4l9o | SCENE= }} | |||
===Crystal Structure of the Sec13-Sec16 blade-inserted complex from Pichia pastoris=== | |||
{{ABSTRACT_PUBMED_24006484}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/SEC13_PICPG SEC13_PICPG]] Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity). | |||
==About this Structure== | |||
[[4l9o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9O OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024006484</ref><references group="xtra"/><references/> | |||
[[Category: Hughson, F M.]] | |||
[[Category: Jeffrey, P D.]] | |||
[[Category: McMahon, C.]] | |||
[[Category: Ace1]] | |||
[[Category: Beta propeller]] | |||
[[Category: Cop-coated vesicle]] | |||
[[Category: Copii]] | |||
[[Category: Endoplasmic reticulum]] | |||
[[Category: Nuclear pore complex protein]] | |||
[[Category: Protein transport]] | |||
[[Category: Vesicle coat budding]] | |||
