4fl9: Difference between revisions
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{{STRUCTURE_4fl9| PDB=4fl9 | SCENE= }} | |||
===Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/HSP7C_BOVIN HSP7C_BOVIN]] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity). | |||
==About this Structure== | |||
[[4fl9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL9 OCA]. | |||
[[Category: Bos taurus]] | |||
[[Category: Grimm, C.]] | |||
[[Category: Heat shock protein]] | |||
[[Category: Transcription]] | |||