4j80: Difference between revisions

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{{STRUCTURE_4j80|  PDB=4j80  |  SCENE=  }}  
{{STRUCTURE_4j80|  PDB=4j80  |  SCENE=  }}  
===Thermus thermophilus DnaJ===
===Thermus thermophilus DnaJ===
{{ABSTRACT_PUBMED_23897477}}


==Function==
==Function==
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==Reference==
==Reference==
<references group="xtra"/><references/>
<ref group="xtra">PMID:023897477</ref><references group="xtra"/><references/>
[[Category: Thermus thermophilus hb8]]
[[Category: Thermus thermophilus hb8]]
[[Category: Barends, T R.M.]]
[[Category: Barends, T R.M.]]

Revision as of 04:52, 10 October 2013

Template:STRUCTURE 4j80

Thermus thermophilus DnaJ

Template:ABSTRACT PUBMED 23897477

Function

[DNAJ2_THET8] Does not influence ATP binding or hydrolysis nor ADP release. Exerts influence on the interaction of DnaK with substrates; in the presence of DafA, DnaJ inhibits substrate binding, and substrate already bound to DnaK is displaced by DnaJ and DafA.[1]

About this Structure

4j80 is a 4 chain structure with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.

Reference

  1. Barends TR, Brosi RW, Steinmetz A, Scherer A, Hartmann E, Eschenbach J, Lorenz T, Seidel R, Shoeman RL, Zimmermann S, Bittl R, Schlichting I, Reinstein J. Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1540-52. doi:, 10.1107/S0907444913010640. Epub 2013 Jul 19. PMID:23897477 doi:https://dx.doi.org/10.1107/S0907444913010640
  1. ↑ Klostermeier D, Seidel R, Reinstein J. The functional cycle and regulation of the Thermus thermophilus DnaK chaperone system. J Mol Biol. 1999 Apr 2;287(3):511-25. PMID:10092456 doi:10.1006/jmbi.1999.2636

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