4lhw: Difference between revisions
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{{STRUCTURE_4lhw| PDB=4lhw | SCENE= }} | |||
===Crystal structure of Rab8 in its active GppNHp-bound form=== | |||
{{ABSTRACT_PUBMED_24072714}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RAB8A_HUMAN RAB8A_HUMAN]] May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization.<ref>PMID:20890297</ref> <ref>PMID:21282656</ref> | |||
==About this Structure== | |||
[[4lhw]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHW OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024072714</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Goody, R S.]] | |||
[[Category: Guo, Z.]] | |||
[[Category: Hou, X M.]] | |||
[[Category: Itzen, A.]] | |||
[[Category: Protein transport]] | |||
[[Category: Small gtpase]] | |||