4f7b: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Structure of the lysosomal domain of limp-2===

The entry ~~4f7b is ON HOLD~~ ~~until Oct 03 2014~~

==Disease==

[[http://www.uniprot.org/uniprot/SCRB2_HUMAN SCRB2_HUMAN]] Unverricht-Lundborg disease;Gaucher disease type 1;Action myoclonus - renal failure syndrome. The disease is caused by mutations affecting the gene represented in this entry. Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.

~~Authors~~: ~~Neculai, D~~.~~, Ravichandran, M~~.~~, Neculai, M., Carlos, J., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Dhe-Paganon, D., Structural Genomics Consortium~~ (~~SGC~~)

==Function==

[[http://www.uniprot.org/uniprot/SCRB2_HUMAN SCRB2_HUMAN]] Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.<ref>PMID:18022370</ref>

~~Description:~~ Structure of a ~~exoplasmic domain of a scavenger~~ receptor

==About this Structure==

[[4f7b]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F7B OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Arrowsmith, C H.]]

[[Category: Bountra, C.]]

[[Category: Dhe-Paganon, D.]]

[[Category: Edwards, A M.]]

[[Category: Neculai, D.]]

[[Category: Neculai, M.]]

[[Category: Pizzaro, J.]]

[[Category: Ravichandran, M.]]

[[Category: SGC, Structural Genomics Consortium.]]

[[Category: Atherosclerosis]]

[[Category: Cell adhesion]]

[[Category: Endocytosis]]

[[Category: Lipid transport]]

[[Category: Lipoprotein]]

[[Category: Scavenger receptor]]

[[Category: Sgc]]

[[Category: Structural genomic]]

[[Category: Structural genomics consortium]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4f7b|  PDB=4f7b  |  SCENE=  }}
+===Structure of the lysosomal domain of limp-2===
-The entry 4f7b is ON HOLD  until Oct 03 2014
+==Disease==
+[[http://www.uniprot.org/uniprot/SCRB2_HUMAN SCRB2_HUMAN]] Unverricht-Lundborg disease;Gaucher disease type 1;Action myoclonus - renal failure syndrome. The disease is caused by mutations affecting the gene represented in this entry.  Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
-Authors: Neculai, D., Ravichandran, M., Neculai, M., Carlos, J., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Dhe-Paganon, D., Structural Genomics Consortium (SGC)
+==Function==
+[[http://www.uniprot.org/uniprot/SCRB2_HUMAN SCRB2_HUMAN]] Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.<ref>PMID:18022370</ref>
-Description: Structure of a exoplasmic domain of a scavenger receptor
+==About this Structure==
+[[4f7b]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F7B OCA].
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Arrowsmith, C H.]]
+[[Category: Bountra, C.]]
+[[Category: Dhe-Paganon, D.]]
+[[Category: Edwards, A M.]]
+[[Category: Neculai, D.]]
+[[Category: Neculai, M.]]
+[[Category: Pizzaro, J.]]
+[[Category: Ravichandran, M.]]
+[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Atherosclerosis]]
+[[Category: Cell adhesion]]
+[[Category: Endocytosis]]
+[[Category: Lipid transport]]
+[[Category: Lipoprotein]]
+[[Category: Scavenger receptor]]
+[[Category: Sgc]]
+[[Category: Structural genomic]]
+[[Category: Structural genomics consortium]]