3m6m: Difference between revisions
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{{STRUCTURE_3m6m| PDB=3m6m | SCENE= }} | {{STRUCTURE_3m6m| PDB=3m6m | SCENE= }} | ||
===Crystal structure of RpfF complexed with REC domain of RpfC=== | ===Crystal structure of RpfF complexed with REC domain of RpfC=== | ||
{{ABSTRACT_PUBMED_20826346}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPFC_XANCP RPFC_XANCP]] Member of the two-component regulatory system RpfG/RpfC, which is required for full virulence and for formation and dispersal of biofilms. Involved in sensing and responding to the diffusible signaling factor (DSF), which is essential for cell-cell signaling. RpfC is probably a sensor of environmental signals, including DSF, which is autophosphorylated at a histidine residue in response to the signal. Then, probably activates RpfG via a four-step phosphorelay. May also negatively regulate the production of DSF, independently of RpfG (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020826346</ref><references group="xtra"/> | <ref group="xtra">PMID:020826346</ref><references group="xtra"/><references/> | ||
[[Category: Histidine kinase]] | [[Category: Histidine kinase]] | ||
[[Category: Xanthomonas campestris pv. campestris]] | [[Category: Xanthomonas campestris pv. campestris]] | ||
Revision as of 06:42, 16 October 2013
Crystal structure of RpfF complexed with REC domain of RpfC
Template:ABSTRACT PUBMED 20826346
Function
[RPFC_XANCP] Member of the two-component regulatory system RpfG/RpfC, which is required for full virulence and for formation and dispersal of biofilms. Involved in sensing and responding to the diffusible signaling factor (DSF), which is essential for cell-cell signaling. RpfC is probably a sensor of environmental signals, including DSF, which is autophosphorylated at a histidine residue in response to the signal. Then, probably activates RpfG via a four-step phosphorelay. May also negatively regulate the production of DSF, independently of RpfG (By similarity).
About this Structure
3m6m is a 6 chain structure with sequence from Xanthomonas campestris pv. campestris. Full crystallographic information is available from OCA.
See Also
Reference
- Cheng Z, He YW, Lim SC, Qamra R, Walsh MA, Zhang LH, Song H. Structural basis of the sensor-synthase interaction in autoinduction of the quorum sensing signal DSF biosynthesis. Structure. 2010 Sep 8;18(9):1199-209. PMID:20826346 doi:10.1016/j.str.2010.06.011
