3hot: Difference between revisions
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{{STRUCTURE_3hot| PDB=3hot | SCENE= }} | {{STRUCTURE_3hot| PDB=3hot | SCENE= }} | ||
===Crystal structure of the Mos1 mariner paired end complex with Mn=== | ===Crystal structure of the Mos1 mariner paired end complex with Mn=== | ||
{{ABSTRACT_PUBMED_19766564}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019766564</ref><references group="xtra"/> | <ref group="xtra">PMID:019766564</ref><references group="xtra"/><references/> | ||
[[Category: Drosophila mauritiana]] | [[Category: Drosophila mauritiana]] | ||
[[Category: Richardson, J M.]] | [[Category: Richardson, J M.]] | ||
Revision as of 06:56, 16 October 2013
Crystal structure of the Mos1 mariner paired end complex with Mn
Template:ABSTRACT PUBMED 19766564
Function
[MOS1T_DROMA] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
About this Structure
3hot is a 8 chain structure with sequence from Drosophila mauritiana. Full crystallographic information is available from OCA.
Reference
- Richardson JM, Colloms SD, Finnegan DJ, Walkinshaw MD. Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote. Cell. 2009 Sep 18;138(6):1096-108. PMID:19766564 doi:10.1016/j.cell.2009.07.012
