4mh5: Difference between revisions
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{{STRUCTURE_4mh5| PDB=4mh5 | SCENE= }} | |||
===Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-glutamate=== | |||
{{ABSTRACT_PUBMED_21907808}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT]] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref> | |||
==About this Structure== | |||
[[4mh5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MH5 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021907808</ref><references group="xtra"/><references/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Frydenvang, K.]] | |||
[[Category: Gajhede, M.]] | |||
[[Category: Kastrup, J S.]] | |||
[[Category: Venskutonyte, R.]] | |||
[[Category: Agonist]] | |||
[[Category: Membrane]] | |||
[[Category: Receptor]] | |||
[[Category: Receptor-agonist complex]] | |||