3zee: Difference between revisions
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{{STRUCTURE_3zee| PDB=3zee | SCENE= }} | |||
===Electron cyro-microscopy helical reconstruction of Par-3 N terminal domain=== | |||
{{ABSTRACT_PUBMED_23643951}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/PARD3_RAT PARD3_RAT]] Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (By similarity). Targets the phosphatase PTEN to cell junctions.<ref>PMID:18082612</ref> <ref>PMID:18550519</ref> | |||
==About this Structure== | |||
[[3zee]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEE OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023643951</ref><references group="xtra"/><references/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Chen, J.]] | |||
[[Category: Feng, W.]] | |||
[[Category: Gao, F.]] | |||
[[Category: Gong, W.]] | |||
[[Category: Sun, F.]] | |||
[[Category: Wang, W.]] | |||
[[Category: Zhang, K.]] | |||
[[Category: Zhang, M.]] | |||
[[Category: Zhang, Y.]] | |||
[[Category: Cell cycle]] | |||