4khn: Difference between revisions
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{{STRUCTURE_4khn| PDB=4khn | SCENE= }} | {{STRUCTURE_4khn| PDB=4khn | SCENE= }} | ||
===Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase=== | ===Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase=== | ||
{{ABSTRACT_PUBMED_24116139}} | |||
==Function== | ==Function== | ||
| Line 7: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[4khn]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHN OCA]. | [[4khn]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHN OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:024116139</ref><references group="xtra"/><references/> | |||
[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Enterobacteria phage rb69]] | [[Category: Enterobacteria phage rb69]] | ||
Revision as of 05:16, 23 October 2013
Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase
Template:ABSTRACT PUBMED 24116139
Function
[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
About this Structure
4khn is a 6 chain structure with sequence from Enterobacteria phage rb69. Full crystallographic information is available from OCA.
Reference
- Jacewicz A, Trzemecka A, Guja KE, Plochocka D, Yakubovskaya E, Bebenek A, Garcia-Diaz M. A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site. PLoS One. 2013 Oct 7;8(10):e76700. doi: 10.1371/journal.pone.0076700. PMID:24116139 doi:https://dx.doi.org/10.1371/journal.pone.0076700