4m9y: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4m9y|  PDB=4m9y  |  SCENE=  }}
===Crystal structure of CED-4 bound CED-3 fragment===
{{ABSTRACT_PUBMED_24065769}}


The entry 4m9y is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/CED4_CAEEL CED4_CAEEL]] Isoform a plays a major role in programmed cell death (PCD, apoptosis). Egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Isoform b prevents PCD.<ref>PMID:1286611</ref> <ref>PMID:8706125</ref> <ref>PMID:9027313</ref> <ref>PMID:10688797</ref> <ref>PMID:15383288</ref> 


Authors: Huang, W.J., Jinag, T.Y., Choi, W.Y., Wang, J.W., Shi, Y.G.
==About this Structure==
[[4m9y]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9Y OCA].  


Description: Crystal structure of CED-4 bound CED-3 fragment
==Reference==
<ref group="xtra">PMID:024065769</ref><references group="xtra"/><references/>
[[Category: Caenorhabditis elegans]]
[[Category: Choi, W Y.]]
[[Category: Huang, W J.]]
[[Category: Jinag, T Y.]]
[[Category: Shi, Y G.]]
[[Category: Wang, J W.]]
[[Category: Apoptosis]]
[[Category: Apoptosome]]