2pgd: Difference between revisions

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New page: left|200px<br /><applet load="2pgd" size="450" color="white" frame="true" align="right" spinBox="true" caption="2pgd, resolution 2.Å" /> '''THE STRUCTURE OF 6-PHO...
 
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[[Image:2pgd.jpg|left|200px]]<br /><applet load="2pgd" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:2pgd.jpg|left|200px]]<br /><applet load="2pgd" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="2pgd, resolution 2.&Aring;" />
caption="2pgd, resolution 2.&Aring;" />
'''THE STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE REFINED AT 2 ANGSTROMS RESOLUTION'''<br />
'''THE STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE REFINED AT 2 ANGSTROMS RESOLUTION'''<br />


==Overview==
==Overview==
The three-dimensional structure of ovine 6-phosphogluconate dehydrogenase, refined at 2.5 A resolution with a residual for all data of 18.5%, is, reported. This model, based on improved diffraction data and a corrected, sequence, supersedes that reported earlier. Each subunit of the dimer has, three domains: a beta-alpha-beta domain binds NADP; an all alpha domain, provides much of the dimer interface; the C-terminal tail burrows into the, second subunit.
The three-dimensional structure of ovine 6-phosphogluconate dehydrogenase, refined at 2.5 A resolution with a residual for all data of 18.5%, is reported. This model, based on improved diffraction data and a corrected sequence, supersedes that reported earlier. Each subunit of the dimer has three domains: a beta-alpha-beta domain binds NADP; an all alpha domain provides much of the dimer interface; the C-terminal tail burrows into the second subunit.


==About this Structure==
==About this Structure==
2PGD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. This structure superseeds the now removed PDB entry 1PGD. Active as [http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(decarboxylating) Phosphogluconate dehydrogenase (decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2PGD OCA].  
2PGD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1PGD. Active as [http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(decarboxylating) Phosphogluconate dehydrogenase (decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGD OCA].  


==Reference==
==Reference==
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[[Category: Phosphogluconate dehydrogenase (decarboxylating)]]
[[Category: Phosphogluconate dehydrogenase (decarboxylating)]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Adams, M.J.]]
[[Category: Adams, M J.]]
[[Category: Gover, S.]]
[[Category: Gover, S.]]
[[Category: Phillips, C.]]
[[Category: Phillips, C.]]
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[[Category: oxidoreductase (choh(d)-nadp+(a))]]
[[Category: oxidoreductase (choh(d)-nadp+(a))]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 13:31:33 2007''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:29:12 2008''