4kp0: Difference between revisions
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{{STRUCTURE_4kp0| PDB=4kp0 | SCENE= }} | |||
===Crystal Structure of the human Chymase with TJK002=== | |||
{{ABSTRACT_PUBMED_24121339}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN]] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. | |||
==About this Structure== | |||
[[4kp0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KP0 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024121339</ref><references group="xtra"/><references/> | |||
[[Category: Chymase]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Kakuda, S.]] | |||
[[Category: Takimoto-Kamimura, M.]] | |||
[[Category: Benzimidazole]] | |||
[[Category: Hydrolase]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Protease]] | |||
[[Category: Serine protease]] | |||
Revision as of 09:31, 30 October 2013
Crystal Structure of the human Chymase with TJK002
Template:ABSTRACT PUBMED 24121339
Function
[CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
About this Structure
4kp0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Matsumoto Y, Kakuda S, Koizumi M, Mizuno T, Muroga Y, Kawamura T, Takimoto-Kamimura M. Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor. J Synchrotron Radiat. 2013 Nov;20(Pt 6):914-8. doi: 10.1107/S0909049513020748., Epub 2013 Sep 25. PMID:24121339 doi:https://dx.doi.org/10.1107/S0909049513020748
