4lpb: Difference between revisions
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{{STRUCTURE_4lpb| PDB=4lpb | SCENE= }} | |||
===Crystal structure of a topoisomerase ATPase inhibitor=== | |||
{{ABSTRACT_PUBMED_24098982}} | |||
==About this Structure== | |||
[[4lpb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LPB OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024098982</ref><references group="xtra"/><references/> | |||
[[Category: Streptococcus pneumoniae r6]] | |||
[[Category: Boriack-Sjodin, A.]] | |||
[[Category: Antimicrobial]] | |||
[[Category: Atp binding]] | |||
[[Category: Atp binding domain]] | |||
[[Category: Isomerase-isomerase inhibitor complex]] | |||
[[Category: Protein-inhibitor complex]] | |||
[[Category: Structure-based drug design]] | |||
[[Category: Virtual screen]] | |||
Revision as of 09:33, 30 October 2013
Crystal structure of a topoisomerase ATPase inhibitor
Template:ABSTRACT PUBMED 24098982
About this Structure
4lpb is a 1 chain structure with sequence from Streptococcus pneumoniae r6. Full crystallographic information is available from OCA.
Reference
- Basarab GS, Manchester JI, Bist S, Boriack-Sjodin PA, Dangel B, Illingworth R, Sherer BA, Sriram S, Uria-Nickelsen M, Eakin AE. Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J Med Chem. 2013 Oct 29. PMID:24098982 doi:https://dx.doi.org/10.1021/jm401208b
