4isa: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4isa|  PDB=4isa  |  SCENE=  }}
===Crystal Structure of the Escherichia coli LpxC/BB-78485 complex===
{{ABSTRACT_PUBMED_24117400}}


The entry 4isa is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/D5CV28_ECOKI D5CV28_ECOKI]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]


Authors: Lee, C.-J., Zhou, P.
==About this Structure==
[[4isa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_ihe3034 Escherichia coli ihe3034]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ISA OCA].  


Description: Crystal Structure of the Escherichia coli LpxC/BB-78485 complex
==Reference==
<ref group="xtra">PMID:024117400</ref><references group="xtra"/><references/>
[[Category: Escherichia coli ihe3034]]
[[Category: Lee, C J.]]
[[Category: Zhou, P.]]
[[Category: Acyl udp-glcnac]]
[[Category: Antibiotic]]
[[Category: Baab sandwich]]
[[Category: Bb-78485]]
[[Category: Deacetylation]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydroxamate]]
[[Category: Lipid a synthesis]]
[[Category: Lpxc]]

Revision as of 09:43, 30 October 2013

Template:STRUCTURE 4isa

Crystal Structure of the Escherichia coli LpxC/BB-78485 complex

Template:ABSTRACT PUBMED 24117400

Function

[D5CV28_ECOKI] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]

About this Structure

4isa is a 1 chain structure with sequence from Escherichia coli ihe3034. Full crystallographic information is available from OCA.

Reference

  1. Lee CJ, Liang X, Gopalaswamy R, Najeeb J, Ark ED, Toone EJ, Zhou P. Structural Basis of the Promiscuous Inhibitor Susceptibility of E. coli LpxC. ACS Chem Biol. 2013 Oct 11. PMID:24117400 doi:https://dx.doi.org/10.1021/cb400067g

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