4j4q: Difference between revisions
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{{STRUCTURE_4j4q| PDB=4j4q | SCENE= }} | |||
===Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside=== | |||
{{ABSTRACT_PUBMED_24038729}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref> [[http://www.uniprot.org/uniprot/GNAT1_BOVIN GNAT1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. | |||
==About this Structure== | |||
[[4j4q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J4Q OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024038729</ref><references group="xtra"/><references/> | |||
[[Category: Bos taurus]] | |||
[[Category: Choe, H W.]] | |||
[[Category: Ernst, O P.]] | |||
[[Category: Hofmann, K P.]] | |||
[[Category: Hong, J E.]] | |||
[[Category: Li, Y.]] | |||
[[Category: Morizumi, T.]] | |||
[[Category: Pai, E F.]] | |||
[[Category: Park, J H.]] | |||
[[Category: G-protein coupled receptor]] | |||
[[Category: Galpha subunit]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Gtp-binding]] | |||
[[Category: Lipoprotein]] | |||
[[Category: Membrane]] | |||
[[Category: Myristate]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Photoreceptor protein]] | |||
[[Category: Receptor retinal protein]] | |||
[[Category: Retinal binding]] | |||
[[Category: Sensory transduction]] | |||
[[Category: Signaling protein]] | |||
[[Category: Transducer]] | |||
[[Category: Transmembrane]] | |||