2yob: Difference between revisions
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{{STRUCTURE_2yob| PDB=2yob | SCENE= }} | |||
===High resolution AGXT_M structure=== | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/SPYA_HUMAN SPYA_HUMAN]] Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1) [MIM:[http://omim.org/entry/259900 259900]]; also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.<ref>PMID:1703535</ref> <ref>PMID:2039493</ref> <ref>PMID:1349575</ref> <ref>PMID:1301173</ref> <ref>PMID:8101040</ref> <ref>PMID:9192270</ref> <ref>PMID:9604803</ref> <ref>PMID:10394939</ref> <ref>PMID:10453743</ref> <ref>PMID:10541294</ref> <ref>PMID:10862087</ref> <ref>PMID:10960483</ref> <ref>PMID:12559847</ref> <ref>PMID:12777626</ref> <ref>PMID:15253729</ref> <ref>PMID:15849466</ref> <ref>PMID:15961946</ref> <ref>PMID:15963748</ref> | |||
==About this Structure== | |||
[[2yob]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YOB OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Albert, A.]] | |||
[[Category: Fabelo-Rosa, I.]] | |||
[[Category: Mesa-Torres, N.]] | |||
[[Category: Pey, A L.]] | |||
[[Category: Riverol, D.]] | |||
[[Category: Salido, E.]] | |||
[[Category: Yunta, C.]] | |||
[[Category: Agxt folding and stability defect]] | |||
[[Category: Primary hyperoxaluria type i]] | |||
[[Category: Transferase]] | |||