4lbe: Difference between revisions
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{{STRUCTURE_4lbe| PDB=4lbe | SCENE= }} | |||
===Structure of KcsA with R122A mutation=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> | |||
==About this Structure== | |||
[[4lbe]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBE OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Streptomyces lividans]] | |||
[[Category: McCoy, J M.]] | |||
[[Category: Nimigean, C M.]] | |||
[[Category: Posson, D J.]] | |||
[[Category: Membrane protein]] | |||
[[Category: Metal transport]] | |||
[[Category: Ph-gated potassium channel]] | |||
[[Category: Transport protein]] | |||
Revision as of 09:52, 30 October 2013
Structure of KcsA with R122A mutation
Function
[KCSA_STRLI] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).[1]
About this Structure
4lbe is a 3 chain structure with sequence from Streptomyces lividans. Full crystallographic information is available from OCA.
