Single stranded binding protein: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 14: Line 14:
<StructureSection load='2vw9' size='400' side='right' frame='true' caption='Structure of Single Stranded DNA-Binding Protein from Helicobacter Pylori bound to ssDNA (PDB entry [[2vw9]])' scene=''>
<StructureSection load='2vw9' size='400' side='right' frame='true' caption='Structure of Single Stranded DNA-Binding Protein from Helicobacter Pylori bound to ssDNA (PDB entry [[2vw9]])' scene=''>


SSB consists is a homotetramer that has a DNA binding domain which binds to a single strand of DNA. The tetramers consist of α-helices, β-sheets, and random coils. Each subunit contains an <scene name='56/566528/Alpha_helices/3'>α-helix</scene> and several <scene name='56/566528/Beta_sheets/1'>β-sheets</scene>. The secondary structure also includes a NH2 terminus, which consists of multiple positively charged amino acids. The COOH terminus includes many acidic amino acids.  
SSB consists is a homotetramer that has a DNA binding domain which binds to a single strand of DNA. The tetramers consist of α-helices, β-sheets, and random coils. Each subunit contains an <scene name='56/566528/Alpha_helices/3'>α-helix</scene> and several <scene name='56/566528/Beta_sheets/1'>β-sheets</scene>. The secondary structure also includes a NH2 terminus, which consists of multiple positively charged amino acids. The DNA-binding domain lies within 115 amino acid residues from this terminus. The COOH terminus includes many acidic amino acids.  


==Binding Interactions in the Active Site==
==Binding Interactions in the Active Site==