Single stranded binding protein: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
Rachel Craig (talk | contribs) No edit summary |
||
| Line 32: | Line 32: | ||
It is believed that Gly15 may play an important role in binding the RecA protein. Mutations in Gly15 have | It is believed that Gly15 may play an important role in binding the RecA protein. Mutations in Gly15 have | ||
extreme effects on recombinational repair. SSB has also been thought to bind with exonuclease I, DNA polymerase II, | extreme effects on recombinational repair. SSB has also been thought to bind with exonuclease I, DNA polymerase II, | ||
and a protein n, which is used to help synthesize RNA primers for the lagging strand. | and a protein n, which is used to help synthesize RNA primers for the lagging strand. SSB can also help regulate transcription by competing with other proteins for binding spaces on DNA. SSB has a higher affinity for DNA than most other proteins, and those proteins are not able to remove SSB from DNA and bind themselves. This type of mechanism can not only regulate transcription, but it can provide protection for the DNA. | ||
</StructureSection> | </StructureSection> | ||
