Single stranded binding protein: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Rachel Craig (talk | contribs) No edit summary |
Rachel Craig (talk | contribs) No edit summary |
||
| Line 17: | Line 17: | ||
====Binding Interactions in the Active Site==== | ====Binding Interactions in the Active Site==== | ||
ssDNA can interact with binding proteins through hydrogen bonds, stacking, or electronegative interactions. | ssDNA can interact with binding proteins through hydrogen bonds, stacking, or electronegative interactions. Most interactions between SSB and ssDNA happen through the OB fold. OB stands for oligosaccharide/oligonucleotide binding site. This fold consists of a 5-stranded β barrel that ends in an α-helix. | ||
<scene name='56/566528/Labeled_phe/1'>Phe56</scene> is an important DNA binding site. It has been shown to be the site for cross-linking. | <scene name='56/566528/Labeled_phe/1'>Phe56</scene> is an important DNA binding site. It has been shown to be the site for cross-linking. | ||
Tryptophan and Lysine residues are important in binding as well. Treatments resulting in | Tryptophan and Lysine residues are important in binding as well. Treatments resulting in | ||
