Ku protein: Difference between revisions
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== Domains == | == Domains == | ||
Consisting of <scene name='56/567269/Ku70_dimer/ | Consisting of <scene name='56/567269/Ku70_dimer/8'>four domains</scene> (α/β-Domain, β-barrel, C-terminal arm, DNA-binding ring), the Ku70 subunit dimerizes with the Ku80 subunit to form the protein.<ref name="Walker"/> | ||
Unlike other DNA binding proteins, the Ku protein is asymmetrical from the differences between the Ku70 and Ku80 subunits. | Unlike other DNA binding proteins, the Ku protein is asymmetrical from the differences between the Ku70 and Ku80 subunits. | ||
This asymmetry leads to different favorable locations for DNA based on major and minor grooves.<ref name="Walker"/> | This asymmetry leads to different favorable locations for DNA based on major and minor grooves.<ref name="Walker"/> | ||