1fmc: Difference between revisions

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===7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID===
===7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID===
{{ABSTRACT_PUBMED_8672472}}
{{ABSTRACT_PUBMED_8672472}}
==Function==
[[http://www.uniprot.org/uniprot/HDHA_ECOLI HDHA_ECOLI]] 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:008672472</ref><references group="xtra"/>
<ref group="xtra">PMID:008672472</ref><references group="xtra"/><references/>
[[Category: 7-alpha-hydroxysteroid dehydrogenase]]
[[Category: 7-alpha-hydroxysteroid dehydrogenase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]

Revision as of 05:57, 6 November 2013

Template:STRUCTURE 1fmc

7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID

Template:ABSTRACT PUBMED 8672472

Function

[HDHA_ECOLI] 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.

About this Structure

1fmc is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Tanaka N, Nonaka T, Tanabe T, Yoshimoto T, Tsuru D, Mitsui Y. Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli. Biochemistry. 1996 Jun 18;35(24):7715-30. PMID:8672472 doi:10.1021/bi951904d

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