4ij3: Difference between revisions
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{{STRUCTURE_4ij3| PDB=4ij3 | SCENE= }} | |||
===Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody=== | |||
{{ABSTRACT_PUBMED_23867277}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/QSOX1_HUMAN QSOX1_HUMAN]] Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation.<ref>PMID:16806532</ref> <ref>PMID:10542195</ref> <ref>PMID:10708601</ref> <ref>PMID:12176051</ref> <ref>PMID:17331072</ref> <ref>PMID:18393449</ref> | |||
==About this Structure== | |||
[[4ij3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IJ3 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023867277</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Mus musculus]] | |||
[[Category: Thiol oxidase]] | |||
[[Category: Fass, D.]] | |||
[[Category: Grossman, I.]] | |||
[[Category: Antibody binding]] | |||
[[Category: Inhibitor]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||