4mjo: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4mjo|  PDB=4mjo  |  SCENE=  }}
===Human liver fructose-1,6-bisphosphatase(d-fructose-1,6-bisphosphate, 1-phosphohydrolase) (e.c.3.1.3.11) complexed with the allosteric inhibitor 3===
{{ABSTRACT_PUBMED_24128068}}


The entry 4mjo is ON HOLD
==Disease==
[[http://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN]] Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:[http://omim.org/entry/229700 229700]]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.<ref>PMID:9382095</ref> <ref>PMID:12126934</ref> 


Authors: Ruf, A., Joseph, C., Tetaz, T., Benz, J.
==About this Structure==
[[4mjo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJO OCA].  


Description: Human liver fructose-1,6-bisphosphatase(d-fructose-1,6-bisphosphate, 1-phosphohydrolase) (e.c.3.1.3.11) complexed with the allosteric inhibitor 3
==Reference==
<ref group="xtra">PMID:024128068</ref><references group="xtra"/><references/>
[[Category: Fructose-bisphosphatase]]
[[Category: Homo sapiens]]
[[Category: Benz, J.]]
[[Category: Joseph, C.]]
[[Category: Ruf, A.]]
[[Category: Tetaz, T.]]
[[Category: Allostery]]
[[Category: Hydrolase-hydrolase inhibitor complex]]