4c51: Difference between revisions
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{{STRUCTURE_4c51| PDB=4c51 | SCENE= }} | |||
===Crystal Structure of the Catalase-Peroxidase (KatG) R418L mutant from Mycobacterium Tuberculosis=== | |||
{{ABSTRACT_PUBMED_24185282}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KATG_MYCTU KATG_MYCTU]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, isoniazid (INH) lyase and isonicotinoyl-NAD synthase activity. May play a role in the intracellular survival of mycobacteria. May be involved in DNA repair. Partly complements recA-deficient E.coli cells exposed to UV radiation, mitomycin C or hydrogen peroxide. Increases resistance to mitomycin C in E.coli cells deficient for either uvrA, uvrB or uvrC.<ref>PMID:10463167</ref> | |||
==About this Structure== | |||
[[4c51]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C51 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024185282</ref><references group="xtra"/><references/> | |||
[[Category: Catalase peroxidase]] | |||
[[Category: Andersson, K K.]] | |||
[[Category: Hersleth, H P.]] | |||
[[Category: Magliozzo, R S.]] | |||
[[Category: Zhao, X.]] | |||
[[Category: Oxidoreductase]] | |||