3nzb: Difference between revisions
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{{STRUCTURE_3nzb| PDB=3nzb | SCENE= }} | {{STRUCTURE_3nzb| PDB=3nzb | SCENE= }} | ||
===Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Potent 5-(omega-carboxyl(alkyloxy)pyrido[2,-d]pyrimidine Derivatives=== | ===Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Potent 5-(omega-carboxyl(alkyloxy)pyrido[2,-d]pyrimidine Derivatives=== | ||
{{ABSTRACT_PUBMED_21206056}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYR_PNECA DYR_PNECA]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==About this Structure== | ==About this Structure== | ||
[[3nzb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3nzb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pneca Pneca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NZB OCA]. | ||
==See Also== | ==See Also== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021206056</ref><references group="xtra"/> | <ref group="xtra">PMID:021206056</ref><references group="xtra"/><references/> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: | [[Category: Pneca]] | ||
[[Category: Cody, V.]] | [[Category: Cody, V.]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
[[Category: Pneumocystius carinii dhfr inhibitor complex]] | [[Category: Pneumocystius carinii dhfr inhibitor complex]] | ||
