3td8: Difference between revisions
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{{STRUCTURE_3td8| PDB=3td8 | SCENE= }} | {{STRUCTURE_3td8| PDB=3td8 | SCENE= }} | ||
===Structural Analysis of Pneumocystis carinii Dihydrofolate Reductase Complex with NADPH and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine=== | ===Structural Analysis of Pneumocystis carinii Dihydrofolate Reductase Complex with NADPH and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine=== | ||
{{ABSTRACT_PUBMED_22505410}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYR_PNECA DYR_PNECA]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==About this Structure== | ==About this Structure== | ||
[[3td8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3td8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pneca Pneca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TD8 OCA]. | ||
==See Also== | ==See Also== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022505410</ref><references group="xtra"/> | <ref group="xtra">PMID:022505410</ref><references group="xtra"/><references/> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: | [[Category: Pneca]] | ||
[[Category: Cody, V.]] | [[Category: Cody, V.]] | ||
[[Category: Pace, J.]] | [[Category: Pace, J.]] | ||