2qdf: Difference between revisions

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New page: left|200px<br /><applet load="2qdf" size="350" color="white" frame="true" align="right" spinBox="true" caption="2qdf, resolution 2.200Å" /> '''Structure of N-term...
 
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==Overview==
==Overview==
Integral beta-barrel proteins are found in the outer membranes of, mitochondria, chloroplasts, and Gram-negative bacteria. The machine that, assembles these proteins contains an integral membrane protein, called, YaeT in Escherichia coli, which has one or more polypeptide, transport-associated (POTRA) domains. The crystal structure of a, periplasmic fragment of YaeT reveals the POTRA domain fold and suggests a, model for how POTRA domains can bind different peptide sequences, as, required for a machine that handles numerous beta-barrel protein, precursors. Analysis of POTRA domain deletions shows which are essential, and provides a view of the spatial organization of this assembly machine.
Integral beta-barrel proteins are found in the outer membranes of mitochondria, chloroplasts, and Gram-negative bacteria. The machine that assembles these proteins contains an integral membrane protein, called YaeT in Escherichia coli, which has one or more polypeptide transport-associated (POTRA) domains. The crystal structure of a periplasmic fragment of YaeT reveals the POTRA domain fold and suggests a model for how POTRA domains can bind different peptide sequences, as required for a machine that handles numerous beta-barrel protein precursors. Analysis of POTRA domain deletions shows which are essential and provides a view of the spatial organization of this assembly machine.


==About this Structure==
==About this Structure==
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Harrison, S.C.]]
[[Category: Harrison, S C.]]
[[Category: Kahne, D.]]
[[Category: Kahne, D.]]
[[Category: Kim, S.]]
[[Category: Kim, S.]]
[[Category: Malinverni, J.C.]]
[[Category: Malinverni, J C.]]
[[Category: Silhavy, T.J.]]
[[Category: Silhavy, T J.]]
[[Category: Sliz, P.]]
[[Category: Sliz, P.]]
[[Category: MG]]
[[Category: MG]]
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[[Category: protein transport]]
[[Category: protein transport]]


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