4bj3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "4bj3" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4bj3| PDB=4bj3 | SCENE= }} | |||
===Integrin alpha2 I domain E318W-collagen complex=== | |||
{{ABSTRACT_PUBMED_23922814}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ITA2_HUMAN ITA2_HUMAN]] Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. | |||
==About this Structure== | |||
[[4bj3]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BJ3 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023922814</ref><references group="xtra"/><references/> | |||
[[Category: Bihan, D.]] | |||
[[Category: Carafoli, F.]] | |||
[[Category: Farndale, R W.]] | |||
[[Category: Hamaia, S W.]] | |||
[[Category: Hohenester, E.]] | |||
[[Category: Cell adhesion]] | |||