4m8o: Difference between revisions
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{{STRUCTURE_4m8o| PDB=4m8o | SCENE= }} | |||
===TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DPOE_YEAST DPOE_YEAST]] DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair.<ref>PMID:12124389</ref> | |||
==About this Structure== | |||
[[4m8o]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8O OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: DNA-directed DNA polymerase]] | |||
[[Category: Hogg, M.]] | |||
[[Category: Johansson, E.]] | |||
[[Category: Osterman, P.]] | |||
[[Category: Sauer-Eriksson, A E.]] | |||
[[Category: Dna polymerase b type]] | |||
[[Category: Dna replication]] | |||
[[Category: Dna synthesis]] | |||
[[Category: Metal-binding]] | |||
[[Category: Nucleotidyltransferase]] | |||
[[Category: Protein-dna complex]] | |||
[[Category: Transferase dna complex]] | |||
[[Category: Transferase-dna complex]] | |||