Sandbox Reserved 761: Difference between revisions
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The Glu binding domains of the monomers are position as such that the rotation about the pivot helix in each monomer is not restricted. The antennae from three subunits within the trimers wrap around each other and undergo conformational changes as the catalytic cleft opens and closes. The antenna serves as an intersubunit communication conduit during negative cooperativity and allosteric regulation. | The Glu binding domains of the monomers are position as such that the rotation about the pivot helix in each monomer is not restricted. The antennae from three subunits within the trimers wrap around each other and undergo conformational changes as the catalytic cleft opens and closes. The antenna serves as an intersubunit communication conduit during negative cooperativity and allosteric regulation. | ||
[[Image:GDH.jpg]] | |||
==Glutamate Dehydrogenase Mechanism== | ==Glutamate Dehydrogenase Mechanism== | ||
