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overall function of Lipocalin family: The lipocalins are a family of proteins which transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids.
overall function of Lipocalin family: The lipocalins are a family of proteins which transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids.
Lipocalins have been associated with many biological processes, among them immune response, pheromone transport, biological prostaglandin synthesis, retinoid binding, and cancer cell interactions.
Lipocalins have been associated with many biological processes, among them immune response, pheromone transport, biological prostaglandin synthesis, retinoid binding, and cancer cell interactions.
wikipedia


short description of protein fold: They share limited regions of sequence homology and a common tertiary structure architecture.[2][3][4][5][6] This is an eight stranded antiparallel beta-barrel with a repeated + 1 topology enclosing an internal ligand binding site.[5][4].<ref>PMID:3125435</ref>
short description of protein fold: They share limited regions of sequence homology and a common tertiary structure architecture.[2][3][4][5][6] This is an eight stranded antiparallel beta-barrel with a repeated + 1 topology enclosing an internal ligand binding site.[5][4].<ref>PMID:3125435</ref>
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===Lipocalin Proteins===
===Lipocalin Proteins===
The merlin-1 protein belongs to the band 4.1 superfamily of membrane-cytoskeletal linkers <ref>PMID:8242753</ref>.
 
Within this superfamily merlin-1 is closer to ezrin,radixin and moesin (the ERM proteins).
ERM proteins link adehrens junctions to the actin cytoskeleton,and are able to remodel adherens junctions during epithelial morphogenesis.
They also maintain the organization of apical surfaces on the plasma membrane <ref>PMID:11329377</ref>.


== Structure of β-LG ==
== Structure of β-LG ==
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==Implications or possible application==
==Implications or possible application==
describe any uses or application that have been made of the protein  
describe any uses or application that have been made of the protein  
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==External Resources==
==External Resources==
* See: [[Oncogenes & Tumor Suppressor Genes]] for Additional examples of oncogenes and tumor suppressor genes.<br />
 
* See: [[Cancer]] for Additional Proteins involved in the disease. <br />
<ref group="xtra">PMID:22525268</ref><ref group="xtra">PMID:12356905</ref><ref group="xtra">PMID:12203111</ref><ref group="xtra">PMID:17134719</ref><ref group="xtra">PMID:14724586</ref><ref group="xtra">PMID:21402777</ref><ref group="xtra">PMID:10847681</ref>
<references group="xtra"/>


== References ==
== References ==