4mwi: Difference between revisions

Revision as of 07:23, 4 December 2013

[MLKL_HUMAN] Required for the execution of programmed necrosis.^[1]

4mwi is a 1 chain structure. Full crystallographic information is available from OCA.

Murphy JM, Lucet IS, Hildebrand JM, Tanzer MC, Young SN, Sharma P, Lessene G, Alexander WS, Babon JJ, Silke J, Czabotar PE. Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL. Biochem J. 2013 Nov 13. PMID:24219132 doi:https://dx.doi.org/10.1042/BJ20131270

↑ Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012 Jan 20;148(1-2):228-43. doi: 10.1016/j.cell.2011.11.030. PMID:22265414 doi:https://dx.doi.org/10.1016/j.cell.2011.11.030

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4mwi|  PDB=4mwi  |  SCENE=  }}
+===Crystal structure of the human MLKL pseudokinase domain===
+{{ABSTRACT_PUBMED_24219132}}
-The entry 4mwi is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/MLKL_HUMAN MLKL_HUMAN]] Required for the execution of programmed necrosis.<ref>PMID:22265414</ref>
-Authors: Czabotar, P.E., Murphy, J.M.
+==About this Structure==
+[[4mwi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWI OCA].
-Description: Crystal structure of the human MLKL pseudokinase domain
+==Reference==
+<ref group="xtra">PMID:024219132</ref><references group="xtra"/><references/>
+[[Category: Czabotar, P E.]]
+[[Category: Murphy, J M.]]
+[[Category: Necroptosis]]
+[[Category: Pseudokinase]]
+[[Category: Transferase]]