Sandbox Reserved 779: Difference between revisions

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β-Lactoglobulin is a small protein, soluble in dilute salt solution as befits a globulin, with 162 amino acid residues (Mr ∼18,400) that fold up into an 8-stranded, antiparallel β-barrel with a 3-turn α-helix on the outer surface and a ninth β-strand flanking the first strand.  
β-Lactoglobulin is a small protein, soluble in dilute salt solution as befits a globulin, with 162 amino acid residues (Mr ∼18,400) that fold up into an 8-stranded, antiparallel β-barrel with a 3-turn α-helix on the outer surface and a ninth β-strand flanking the first strand.  
===Background ===
β-Lactoglobulin belongs to the calycin superfamily and Lipocalin family.




===Lipocalin Proteins===
===Lipocalin Proteins===
Lipocalins are typically small (160-180 residues in length), extracellular proteins sharing several common molecular recognition properties: the binding of small, principally hydrophobic molecules (such as retinol); binding to specific cell-surface receptors; and the formation of covalent and non-covalent complexes with other soluble macromolecules. Although they have been classified mainly as transport proteins  
β-Lactoglobulin belongs to the calycin superfamily and Lipocalin family. Lipocalins are typically small (160-180 residues in length), extracellular proteins sharing several common molecular recognition properties: the binding of small, principally hydrophobic molecules (such as retinol); binding to specific cell-surface receptors; and the formation of covalent and non-covalent complexes with other soluble macromolecules. Although they have been classified mainly as transport proteins  
<ref>PMID:11058743</ref>
<ref>PMID:11058743</ref>


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==Other β-Lactoglobulin related 3D Structures and complexes==
==Other β-Lactoglobulin related 3D Structures and complexes==


[[2q2m]] - Bovine Beta-Lactoglobulin Native
[[2q2m]] - Bovine Beta-Lactoglobulin Native (Fig. 2)


[[1b8e]] - Crystal structure of the Bovine beta-Lactoglobulin (Isoforms A and B) in orthorombic space group
[[1b8e]] - Crystal structure of the Bovine beta-Lactoglobulin (Isoforms A and B) in orthorombic space group