Sandbox Reserved 764: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 58: | Line 58: | ||
===Addition-Elimination Reaction=== | ===Addition-Elimination Reaction=== | ||
The transfer of the phosphoenolpyruvyl group occurs via an addition elimination reaction. The nucleophilic hydroxyl group of S3P attacks PEP's partially positive C-2. This attack results in the release of inorganic phosphate as a leaving group. | The transfer of the phosphoenolpyruvyl group occurs via an addition elimination reaction <ref>PMID:17348837</ref>. The nucleophilic hydroxyl group of S3P attacks PEP's partially positive C-2. This attack results in the release of inorganic phosphate as a leaving group. Recent studies suggest that there is an intermediate formed in which ketal by-products are formed for use in other pathways. However, more research is necessary to determine the extent to which all of S3P is converted to 5-enolpyruvylshikimate-3-phosphate <ref>PMID:17348837</ref>. | ||
[[Image:EPSP.jpg]] | [[Image:EPSP.jpg]] | ||
